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Protriptyline hydrochloride

CAS No. 1225-55-4

Protriptyline hydrochloride ( —— )

产品货号. M10865 CAS No. 1225-55-4

Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA).

纯度: >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
10MG ¥340 有现货
25MG ¥737 有现货
50MG ¥1264 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Protriptyline hydrochloride
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA).
  • 产品描述
    Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, protriptyline does not affect mood or arousal, but may cause sedation. In depressed individuals, protriptyline exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake. In addition, TCAs down-regulate cerebral cortical β-adrenergic receptors and sensitize post-synaptic serotonergic receptors with chronic use. The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. TCAs also block histamine H1 receptors, α1-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred vision, dry mouth, constipation, urinary retention), respectively. See toxicity section below for a complete listing of side effects. Protriptyline may be used for the treatment of depression.
  • 同义词
    ——
  • 通路
    Endocrinology/Hormones
  • 靶点
    5-HT Receptor
  • 受体
    Sert (Sodium-dependent)
  • 研究领域
    Neurological Disease
  • 适应症
    ——

化学信息

  • CAS Number
    1225-55-4
  • 分子量
    299.84
  • 分子式
    C19H21N·HCl
  • 纯度
    >98%(HPLC)
  • 溶解度
    Soluble in DMSO
  • SMILES
    Cl.CNCCCC1C2=CC=CC=C2C=CC2=CC=CC=C12
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.McDougle CJ, et al. Mol Psychiatry. 1998 May;3(3):270-3.
产品手册
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