Protriptyline hydrochloride
CAS No. 1225-55-4
Protriptyline hydrochloride ( —— )
产品货号. M10865 CAS No. 1225-55-4
Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA).
纯度: >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
10MG | ¥340 | 有现货 |
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25MG | ¥737 | 有现货 |
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50MG | ¥1264 | 有现货 |
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100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Protriptyline hydrochloride
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA).
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产品描述Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, protriptyline does not affect mood or arousal, but may cause sedation. In depressed individuals, protriptyline exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake. In addition, TCAs down-regulate cerebral cortical β-adrenergic receptors and sensitize post-synaptic serotonergic receptors with chronic use. The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. TCAs also block histamine H1 receptors, α1-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred vision, dry mouth, constipation, urinary retention), respectively. See toxicity section below for a complete listing of side effects. Protriptyline may be used for the treatment of depression.
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同义词——
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通路Endocrinology/Hormones
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靶点5-HT Receptor
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受体Sert (Sodium-dependent)
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研究领域Neurological Disease
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适应症——
化学信息
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CAS Number1225-55-4
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分子量299.84
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分子式C19H21N·HCl
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纯度>98%(HPLC)
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溶解度Soluble in DMSO
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SMILESCl.CNCCCC1C2=CC=CC=C2C=CC2=CC=CC=C12
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.McDougle CJ, et al. Mol Psychiatry. 1998 May;3(3):270-3.
产品手册
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